Dataset ID | Dataset Description | Paper Title | Citation | Organism | Conditions (#) | Cell (#) | File Size (Gb) | BAM | BAI |
E-MTAB-2512 | T helper 2 (Th2) cells | Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis. | Mahata ... Teichmann Cell Reports 2014 | Mus musculus (mm10) | 1 | 91 | 190.2 |
E-MTAB-3346 | Mouse medullary thyme ephitelial cells (mTECs) - mature (MHCIIhi) mTECs and 3 subsets selected for their particular tissue-restricted self antigens | Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells | Brennecke ... Steinmetz Nature Immunology 2015 | Mus musculus (mm10) | 4 | 293 | 210.6 |
1. MHCII_high_Ceacam1 | 33 | 29.9 | ||||||||||||
2. MHCII_high_Tspan8 | 49 | 36.2 | ||||||||||||
3. MHCII_high | 163 | 115.6 | ||||||||||||
4. MHCII_low | 48 | 28.9 | ||||||||||||
E-MTAB-3857 | CD4+ T lymphocytes from uninfected mouse and 3 mice with Salmonella typhimurium infection (2 at day 14, 1 at day 49 post-infection) | T cell fate and clonality inference from single-cell transcriptomes | Stubbington ... Teichmann Nature Methods 2016 | Mus musculus (mm10) | 3 | 272 | 157.9 |
1. day_0 | 50 | 35.7 | ||||||||||||
2. day_14 | 110 | 62.2 | ||||||||||||
3. day_49 | 112 | 60 | ||||||||||||
E-MTAB-4619 | CD4 T-helper cells from 3 sites, 5 days after Nippostrongylus brasiliensis infection | Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation | Proserpio ... Teichmann Genome Biology 2016 | Mus musculus (mm10) | 3 | 210 | 21.5 |
1. mediastinal_lymph_nodes | 68 | 7.2 | ||||||||||||
2. mesenteric_lymph_nodes | 68 | 6.3 | ||||||||||||
3. lung | 74 | 8 | ||||||||||||
ERP010829 | Wildtype and Bcl11a deficient haematopoietic stem cells (HSC) | Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells. | Tsang ... Liu Genome Biology 2015 | Mus musculus (mm10) | 3 | 288 | 185.3 |
1. 8wk_WT | 96 | 85 | ||||||||||||
2. BL6_HSC | 96 | 24.4 | ||||||||||||
3. Mut_HSC | 96 | 75.8 | ||||||||||||
GSE48968 | Primary mouse dendritic cells (DCs) stimulated with three pathogenic components (LPS, PAM, PIC) at different time points after stimulation (0h,1h, 2h, 4h, 6h) | Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. | Shalek ... Regev Nature 2014 | Mus musculus (mm10) | 24 | 2412 | 1296 |
1. Ifnar1_KO_LPS_2h | 61 | 18.2 | ||||||||||||
2. Ifnar1_KO_LPS_4h | 96 | 25.8 | ||||||||||||
3. IFNB_2h | 94 | 59.1 | ||||||||||||
4. LPS_1h | 96 | 84.7 | ||||||||||||
5. LPS_2h | 220 | 130.3 | ||||||||||||
6. LPS_4h_GolgiPlug_0h | 56 | 18.3 | ||||||||||||
7. LPS_4h_GolgiPlug_1h | 46 | 11 | ||||||||||||
8. LPS_4h_GolgiPlug_2h | 53 | 9.3 | ||||||||||||
9. LPS_4h | 328 | 248.4 | ||||||||||||
10. LPS_4h_Tenth | 49 | 23.9 | ||||||||||||
11. LPS_6h | 96 | 70.1 | ||||||||||||
12. On_Chip_Stimulation_LPS_4h | 90 | 17.6 | ||||||||||||
13. On_Chip_Unstim | 38 | 9.5 | ||||||||||||
14. PAM_1h | 96 | 64.4 | ||||||||||||
15. PAM_2h | 96 | 61.4 | ||||||||||||
16. PAM_4h | 85 | 42.7 | ||||||||||||
17. PAM_6h | 64 | 34.8 | ||||||||||||
18. PIC_1h | 96 | 70.3 | ||||||||||||
19. PIC_2h | 84 | 61.9 | ||||||||||||
20. PIC_4h | 90 | 67.5 | ||||||||||||
21. PIC_6h | 96 | 16.3 | ||||||||||||
22. Stat1_KO_LPS_4h | 94 | 12.7 | ||||||||||||
23. Tnfr_KO_LPS_4h | 96 | 17.6 | ||||||||||||
24. Unstimulated | 192 | 120.2 | ||||||||||||
GSE54006 | Dendritic cells and additional hematopoietic cell types in steady state and after pathogen activation (LPS) | Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. | Jaitin ... Amit Science 2014 | Mus musculus (mm10) | 13 | 4468 | 30.1 |
1. B_cell | 48 | 0.6 | ||||||||||||
2. CD8+CD86- | 95 | 1.4 | ||||||||||||
3. CD8+CD86+ | 95 | 0.9 | ||||||||||||
4. CD8+pDC | 95 | 0.1 | ||||||||||||
5. CD8-CD4+ESAM+ | 95 | 1.9 | ||||||||||||
6. CD8-pDC | 95 | 1.9 | ||||||||||||
7. GC_B_cell | 47 | 1 | ||||||||||||
8. CD11c+ | 701 | 13.4 | ||||||||||||
9. CD11c+_LPS | 1528 | 4 | ||||||||||||
10. CD11c+_PBS | 1528 | 3.6 | ||||||||||||
11. monocyte_or_neutrophil | 47 | 0.6 | ||||||||||||
12. NK_cell | 47 | 0.4 | ||||||||||||
13. splenocyte | 47 | 0.5 | ||||||||||||
GSE59114 | Long-term hematopoietic stem cells (LT-HSC), short-term hematopoietic stem cells (ST-HSCs), and multipotent progenitors (MPPs) from two mouse strains (C57BL/6 and DBA/2) from young and old mice | Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. | Kowalczyk ... Regev Genome Research 2015 | Mus musculus (mm10) | 12 | 2089 | 252.1 |
1. old_C57BL6_LTHSC | 384 | 57.8 | ||||||||||||
2. old_C57BL6_MPP | 192 | 30 | ||||||||||||
3. old_C57BL6_STHSC | 384 | 49.4 | ||||||||||||
4. old_DBA_LTHSC | 140 | 7.9 | ||||||||||||
5. old_DBA_MPP | 70 | 4.1 | ||||||||||||
6. old_DBA_STHSC | 68 | 3.7 | ||||||||||||
7. young_C57BL6_LTHSC | 192 | 29.7 | ||||||||||||
8. young_C57BL6_MPP | 192 | 33.5 | ||||||||||||
9. young_C57BL6_STHSC | 192 | 22.7 | ||||||||||||
10. young_DBA_LTHSC | 115 | 5.3 | ||||||||||||
11. young_DBA_MPP | 89 | 4.5 | ||||||||||||
12. young_DBA_STHSC | 71 | 3.6 | ||||||||||||
GSE60297 | Mature (MHCII high) medullary thymic epithelial cells (mTEC) | Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. | Sansom SN ... Hollander GA Genome Research 2014 | Mus musculus (mm10) | 1 | 174 | 49 |
GSE60781 | Macrophage DC progenitor (MDP), common DC progenitor (CDP), and pre-DC | Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow | Schlitzer ... Ginhoux Nature Immunology 2015 | Mus musculus (mm10) | 3 | 251 | 22.1 |
1. MDP | 59 | 7.7 | ||||||||||||
2. CDP | 96 | 7.2 | ||||||||||||
3. Pre-DC | 96 | 7.2 | ||||||||||||
GSE61533 | Haematopoietic stem cells (HSC) | Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations. | Wilson ... Gottgens Cell Stem Cell 2015 | Mus musculus (mm10) | 1 | 96 | 32.1 |
GSE64002 | Hematopoietic stem and progenitor cells from bone marrow cells | Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors. | Haas ... Essers Cell Stem Cell 2015 | Mus musculus (mm10) | 2 | 20 | 18.7 |
1. cd150minus | 11 | 10.4 | ||||||||||||
2. cd150plus | 9 | 8.3 | ||||||||||||
GSE65528 | Macrophages at 4 time points after Salmonella exposure | Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses. | Avraham ... Hung Cell 2015 | Mus musculus (mm10) | 10 | 192 | 27.8 |
1. time_0 | 24 | 3.7 | ||||||||||||
2. time_2.5 | 16 | 2 | ||||||||||||
3. time_2.5_pHrodo | 16 | 2.2 | ||||||||||||
4. time_2.5_pHrodo_GFP | 16 | 2 | ||||||||||||
5. time_4 | 24 | 3.6 | ||||||||||||
6. time_4_pHrodo | 24 | 4.1 | ||||||||||||
7. time_4_pHrodo_GFP | 24 | 3.6 | ||||||||||||
8. time_8 | 16 | 2 | ||||||||||||
9. time_8_pHrodo | 16 | 2.4 | ||||||||||||
10. time_8_pHrodo_GFP | 16 | 2.3 | ||||||||||||
GSE65529 | Macrophages at 4 time points after LPS exposure | Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses. | Avraham ... Hung Cell 2015 | Mus musculus (mm10) | 5 | 96 | 12.7 |
1. time_0 | 24 | 2.4 | ||||||||||||
2. time_4_No_No | 18 | 2.2 | ||||||||||||
3. time_4_No_Yes | 18 | 1.8 | ||||||||||||
4. time_4_Yes_No | 18 | 3.9 | ||||||||||||
5. time_4_Yes_Yes | 18 | 2.4 | ||||||||||||
GSE67120 | Several mouse cell populations closely related to HSC formation | Tracing haematopoietic stem cell formation at single-cell resolution. | Zhou ... Liu Nature 2016 | Mus musculus (mm10) | 8 | 181 | 115.3 |
1. Adult_HSC | 30 | 18.6 | ||||||||||||
2. E12_FL | 21 | 11.1 | ||||||||||||
3. E14_FL | 16 | 11.2 | ||||||||||||
4. EC | 17 | 12.5 | ||||||||||||
5. T1CD201neg | 21 | 15.3 | ||||||||||||
6. T1 | 28 | 14.6 | ||||||||||||
7. T2_CD41low | 26 | 16.5 | ||||||||||||
8. T2 | 22 | 15.4 | ||||||||||||
GSE70657 | Young (2-3 months) and old (20-25 months) mouse HSCs | Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cell | Grover ... Nerlov Nature Communications 2016 | Mus musculus (mm10) | 2 | 135 | 31.9 |
1. young | 61 | 16.5 | ||||||||||||
2. old | 74 | 15.4 | ||||||||||||
GSE70798 | Wildtype and AireKO thymic epithelial cells | Aire controls gene expression in the thymic epithelium with ordered stochasticity. | Meredith ... Benoist Nature Immunology 2015 | Mus musculus (mm10) | 2 | 200 | 4.4 |
1. Aire_KO_AireGFP | 100 | 2.2 | ||||||||||||
2. WT_AireGFP | 100 | 2.2 | ||||||||||||
GSE72857 | Bone marrow myeloid progenitors | Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors. | Paul ... Amit Cell 2015 | Mus musculus (mm10) | 8 | 10260 | 48.7 |
1. Cebpa_control | 1140 | 6.4 | ||||||||||||
2. Cebpa_KO | 2280 | 11.4 | ||||||||||||
3. Cebpe_control | 380 | 2 | ||||||||||||
4. Cebpe_KO | 760 | 3.5 | ||||||||||||
5. CMP_CD41 | 380 | 1.1 | ||||||||||||
6. CMP_Flt3+_Csf1r+ | 1140 | 5.3 | ||||||||||||
7. CMP_Irf8-GFP+_MHCII+ | 1140 | 9.1 | ||||||||||||
8. Unsorted_myeloid | 3040 | 9.9 | ||||||||||||
GSE74833 | Th17 cell pathogenicity. SubSeries: GSE75107, GSE75108, GSE75109, GSE75110, GSE75111 | Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. | Gaublomme ... Regev Cell 2015 | Mus musculus (mm10) | 5 | 722 | 324.6 |
1. EAE-CNS-IL-17A_GFP+ (GSE75107) | 166 | 95.1 | ||||||||||||
2. EAE-LN-IL-17A_GFP+ (GSE75108) | 136 | 55.2 | ||||||||||||
3. IL1B_IL6_IL23-48h-IL-17A_GFP+ (GSE75109) | 139 | 47.2 | ||||||||||||
4. TGFB1_IL6-48h (GSE75110) | 130 | 62.5 | ||||||||||||
5. TGFB1_IL6-48h-IL-17A_GFP+ (GSE75111) | 151 | 64.6 | ||||||||||||
GSE74923 | Lymphocytic leukemia cell line (L1210) and CD8 T cells | A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages. | Kimmerling ... Manalis Nature Communications 2016 | Mus musculus (mm10) | 2 | 194 | 14.6 |
1. Lymphocytic leukemia cell line (L1210) | 88 | 4.7 | ||||||||||||
2. CD8 T cells | 106 | 10 | ||||||||||||
GSE81682 | Haematopoeitic stem and progenitor cells | A single cell resolution map of mouse haematopoietic stem and progenitor cell differentiation. | Nestorowa ... Gottgens Blood 2016 | Mus musculus (mm10) | 3 | 1920 | 662.6 |
1. Haematopoietic progenitor cell Prog (HPCP) | 852 | 361.8 | ||||||||||||
2. Haematopoietic stem cell/multipotent progenitor HSPC (HSC) | 852 | 228.7 | ||||||||||||
3. Long term haematopoeitic stem cells (LT-HSC) | 216 | 72.1 | ||||||||||||
GSE68981 | HSC and MPPs from normal and bled mice | Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors | Yang ... Weissman Nucleic Acids Research 2016 | Mus musculus (mm10) | 4 | 460 | 85 |
1. bled_HSC | 53 | 13.8 | ||||||||||||
2. HSC | 221 | 43.1 | ||||||||||||
3. bled_MPP1 | 63 | 18 | ||||||||||||
4. MPP1 | 123 | 10.2 | ||||||||||||
GSE71794 | Murine hematopoietic stem cells, ESC, and HSC-like cells derived from differentiation of embryonic stem cells | Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity | Lu ... Daley Cell Reports 2016 | Mus musculus (mm10) | 4 | 316 | 23.8 |
1. Eng_BM-HSC | 95 | 2.9 | ||||||||||||
2. Eng_ES-HSC | 49 | 1.5 | ||||||||||||
3. ESC | 78 | 3.8 | ||||||||||||
4. FL_HSC | 94 | 15.5 | ||||||||||||
E-MTAB-4825 | Mouse B cells early class switching of IgE | Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE | Wu ... Rada JEM 2016 | Mus musculus (mm10) | 5 | 213 | 50.2 |
1. GFP_female | 65 | 10.9 | ||||||||||||
2. GFP_male | 25 | 10 | ||||||||||||
3. neg_female | 41 | 7 | ||||||||||||
4. Tom_female | 51 | 7.8 | ||||||||||||
5. Tom_male | 31 | 14.5 | ||||||||||||
GSE74596 | Mouse Va14 iNKT thymocyte subsets | Innate-like functions of natural killer T cell subsets result from highly divergent gene programs | Engel ... Kronenberg Nature Immunology 2016 | Mus musculus (mm10) | 4 | 203 | 51.7 |
1. NKT0 | 45 | 10.5 | ||||||||||||
2. NKT1 | 46 | 10.3 | ||||||||||||
3. NKT17 | 44 | 8.1 | ||||||||||||
4. NKT2 | 68 | 22.9 | ||||||||||||
ERP011804 | Transcriptional regulatory network during ILC2 commitment | Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway | Yu ... Liu Nature 2016 | Mus musculus (mm10) | 1 | 768 | 129.4 |
GSE77740 | LMPP isolated from the bone marrow of 4mo and 14mo wild-type C57BL/6J female mice | Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging | Young ... Trowbridge JEM 2016 | Mus musculus (mm10) | 2 | 167 | 63.5 |
1. LMPP_4_month | 84 | 19.2 | ||||||||||||
2. LPMM_14_month | 83 | 44.3 | ||||||||||||
GSE90486 | Myeloid cells infected with lentiviral vectors carrying different gRNAs | Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq | Jaitin ... Amit Cell 2016 | Mus musculus (mm10) | 14 | 23808 | 91 |
1. dendritic_spleen_GFP+BFP+CD3-TCRb-CD19-NK-1.1-Ly6g-CD11c++LPS_in_vivo_mix_BFP | 768 | 2.8 | ||||||||||||
2. myeloid_bone_marrow_GFP+BFP+_mCherry+CD11c++unstimulated_Cebpb_BFP_x_Rela_mCherry | 384 | 1.9 | ||||||||||||
3. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_Cebpb_BFP_x_Rela_mCherry | 768 | 2.2 | ||||||||||||
4. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_developmental_genes_mix_BFP | 1152 | 4.7 | ||||||||||||
5. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_INF_AV_gRNA_pool_BFP | 6144 | 21.5 | ||||||||||||
6. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_INF_AV_mix1_BFP | 4224 | 16 | ||||||||||||
7. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_INF_AV_mix2_BFP | 4224 | 18.2 | ||||||||||||
8. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_Irf9_x_Rela_BFP | 1152 | 4.9 | ||||||||||||
9. myeloid_bone_marrow_GFP+BFP+CD11c++LPS_Itgam-BFP_x_Cebpb-mCherry | 384 | 1.2 | ||||||||||||
10. myeloid_bone_marrow_GFP+BFP+CD11c++unstimulated_Cebpb_BFP | 384 | 2.2 | ||||||||||||
11. myeloid_bone_marrow_GFP+BFP+CD11c++unstimulated_Cebpb_BFP_x_Rela_mCherry | 1152 | 4.6 | ||||||||||||
12. myeloid_bone_marrow_GFP+BFP+CD11c++unstimulated_control_gRNA | 384 | 1.9 | ||||||||||||
13. myeloid_bone_marrow_GFP+BFP+CD11c++unstimulated_Itgam-BFP_x_Cebpb-mCherry | 384 | 1 | ||||||||||||
14. myeloid_spleen_GFP+BFP+CD3-TCRb-CD19-NK-1.1-Ly6g-+LPS_in_vivo_mix_BFP | 2304 | 7.9 | ||||||||||||
GSE70245 | CMP. SubSeries: GSE70236, GSE70238, GSE70239, GSE70240, GSE70241, GSE70242, GSE70243, GSE70244, GSE78907 | Single-cell analysis of mixed-lineage states leading to a binary cell fate choice | Olsson ... Grimes Nature 2016 | Mus musculus (mm10) | 9 | 660 | 240.9 |
1. CMP | 96 | 39.9 | ||||||||||||
2. Gfi1-GFP_GMP | 39 | 18.7 | ||||||||||||
3. Gfi1-_GMP | 80 | 19.4 | ||||||||||||
4. GMP | 136 | 51.3 | ||||||||||||
5. Irf8-GFP_GMP | 37 | 15.1 | ||||||||||||
6. Irf8_KO_GMP | 63 | 14.7 | ||||||||||||
7. LK_CD34 | 66 | 20.4 | ||||||||||||
8. LSK | 96 | 41.6 | ||||||||||||
9. Gfi1-_Irf8-_GMP | 47 | 19.9 | ||||||||||||
GSE85152 | Small intestinal ILCs (Innate lymphoid cells) | The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome | Gury-BenAri ... Amit Cell 2016 | Mus musculus (mm10) | 3 | 2701 | 26.4 |
1. gut_ILC | 1282 | 9.4 | ||||||||||||
2. gut_ILC_GF | 1108 | 13.7 | ||||||||||||
3. gut_ILC_NoGFP | 311 | 3.3 | ||||||||||||
E-MTAB-4888 | CD4+ T cells from young and old mice of CAST/EiJ and C57BL/6 | Aging increases cell-to-cell transcriptional variability upon immune stimulation | Eling ... Odom Science 2017 | Mus musculus (mm10) | 11 | 1506 | 544.9 |
1. B6_o_memory_anti_CD3e_CD28 | 55 | 17.3 | ||||||||||||
2. B6_o_memory_none | 133 | 43.8 | ||||||||||||
3. B6_o_naive_anti_CD3e_CD28 | 236 | 106.7 | ||||||||||||
4. B6_o_naive_none | 422 | 152.6 | ||||||||||||
5. B6_y_memory_anti_CD3e_CD28 | 174 | 19.6 | ||||||||||||
6. B6_y_naive_anti_CD3e_CD28 | 92 | 46.5 | ||||||||||||
7. B6_y_naive_none | 196 | 75.1 | ||||||||||||
8. CAST_o_naive_anti_CD3e_CD28 | 59 | 27.7 | ||||||||||||
9. CAST_o_naive_none | 69 | 26.3 | ||||||||||||
10. CAST_y_naive_anti_CD3e_CD28 | 35 | 16.4 | ||||||||||||
11. CAST_y_naive_none | 35 | 12.9 | ||||||||||||
GSE86042 | CD8 TILs from WT and MTKO mice. SubSeries: GSE86028, GSE86030, GSE86031, GSE86039 | A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells | Singer ... Anderson Cell 2016 | Mus musculus (mm10) | 2 | 1061 | 109 |
1. WT | 516 | 50 | ||||||||||||
2. MTKO | 545 | 59.1 | ||||||||||||
ERP015644 | CD4 T cells 7 days after infection or immunisation | Opposing Development of Cytotoxic and Follicular Helper CD4?? T Cells Controlled by the TCF-1-Bcl6 Nexus | Donnarumma ... Kassiotis Cell Reports 2016 | Mus musculus (mm10) | 4 | 567 | 67 |
1. BCL6_Ad5 | 96 | 12 | ||||||||||||
2. BCL6_FV | 96 | 12.8 | ||||||||||||
3. WT_Ad5 | 190 | 22.8 | ||||||||||||
4. WT_FV | 185 | 19.5 | ||||||||||||
ERP005546 | Activated T helper cells | No Publication | ... The Wellcome Trust Sanger Institute 2016 | Mus musculus (mm10) | 2 | 262 | 82.7 |
1. mesLN | 100 | 22.1 | ||||||||||||
2. spleen | 162 | 60.6 | ||||||||||||
E-MTAB-4388 | transcriptional states of individual CD4+ T cells during blood-stage Plasmodium chabaudi infection in mice. | Single-cell? RNA-seq? and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria | Lonnberg ... Teichmann Sci Immunol. 2017 | Mus musculus (mm10) | 12 | 1598 | 566 |
1. Dendritic_3d_Plasmodium | 39 | 6 | ||||||||||||
2. Dendritic_CD8a-_0d_none | 50 | 21.8 | ||||||||||||
3. Dendritic_CD8a+_0d_none | 46 | 26.4 | ||||||||||||
4. Monocyte_0d_none | 96 | 52.7 | ||||||||||||
5. Monocyte_3d_Plasmodium | 79 | 36.5 | ||||||||||||
6. Tcell_0d_none | 362 | 91.5 | ||||||||||||
7. Tcell_2d_Plasmodium | 135 | 61.4 | ||||||||||||
8. Tcell_3d_Plasmodium | 21 | 10.7 | ||||||||||||
9. Tcell_4d_Plasmodium | 281 | 125 | ||||||||||||
10. Tcell_7d_naive | 89 | 19.2 | ||||||||||||
11. Tcell_7d_none | 143 | 40.4 | ||||||||||||
12. cell_7d_Plasmodium | 257 | 75 | ||||||||||||
GSE90799 | Molecular reprogramming of granulocyte/macrophage progenitor (GMP) clusters. SubSeries: GSE90797, GSE90140 | Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. | Herault ... Passegue Nature 2017 | Mus musculus (mm10) | 7 | 958 | 63.9 |
1. Day0 | 96 | 5.9 | ||||||||||||
2. Day8 | 190 | 12.9 | ||||||||||||
3. Day10 | 96 | 6.3 | ||||||||||||
4. Day12 | 96 | 5.9 | ||||||||||||
5. Day14 | 96 | 2.9 | ||||||||||||
6. control | 96 | 7.7 | ||||||||||||
7. BCR_ABL | 288 | 22.2 | ||||||||||||
GSE98048 | Single-cell comparison of vehicle (control) and HDAC inhibitor (ricolinostat)-treated tumor infiltrating T cells and macrophages | Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer. | Adeegbe ... Wong Cancer Discov. 2017 | Mus musculus (mm10) | 4 | 192 | 1.3 |
1. Macrophage_ACY1215 | 32 | 0.3 | ||||||||||||
2. Macrophage_Vehicle | 32 | 0.3 | ||||||||||||
3. Tcell_ACY1215 | 64 | 0.3 | ||||||||||||
4. Tcell_Vehicle | 64 | 0.4 | ||||||||||||
GSE107910 | A single-cell atlas of the developing mouse thymus | A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation | Kernfeld ... Maehr Immunity 2018 | Mus musculus (mm10) | 11 | 24279 | 55.1 |
1. E12_5_wholeThy_venus | 1747 | 7.8 | ||||||||||||
2. E13_5_wholeThy | 3769 | 8.8 | ||||||||||||
3. E14_5_wholeThy | 1654 | 5.2 | ||||||||||||
4. E15_5_wholeThy | 1506 | 4.5 | ||||||||||||
5. E16_5_wholeThy | 2831 | 3.9 | ||||||||||||
6. E17_5_wholeThy | 2036 | 5.4 | ||||||||||||
7. E18_5_wholeThy | 913 | 2.6 | ||||||||||||
8. FTOC_PBSDMSO | 3660 | 4.2 | ||||||||||||
9. FTOC_RA | 3178 | 7.2 | ||||||||||||
10. P0_wholeThy | 973 | 2.6 | ||||||||||||
11. Rag1KO_wholeThy | 2012 | 2.9 | ||||||||||||
GSE98969 | Transcriptional profiling of single cells from immune populations of mouse models of neurodegenerative diseases with matched controls | A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease. | Keren-Shaul ... Amit Cell 2017 | Mus musculus (mm10) | 28 | 35242 | 94.8 |
1. Cerebellum_5XFAD_CD45+_Alzheimer_disease_6_months | 2280 | 6.3 | ||||||||||||
2. Cerebellum_C57BL_CD45+_Alzheimer_disease_6_months | 1520 | 4 | ||||||||||||
3. Cortex_5XFAD_CD45+_Alzheimer_disease_6_months | 2280 | 6.4 | ||||||||||||
4. Cortex_C57BL_CD45+_Alzheimer_disease_6_months | 1520 | 4 | ||||||||||||
5. Spinal_cord_C57BL_CD45+_ALS_135_days | 760 | 1.9 | ||||||||||||
6. Spinal_cord_C57BL_CD45+_ALS_80_days | 1712 | 3.7 | ||||||||||||
7. Spinal_cord_SOD1_CD45+_ALS_135_days | 760 | 1.6 | ||||||||||||
8. Spinal_cord_SOD1_CD45+_ALS_80_days | 2280 | 4.6 | ||||||||||||
9. Whole_brain_5XFAD_CD45+_Alzheimer_disease_6_months | 6080 | 14.1 | ||||||||||||
10. Whole_brain_5XFAD_CD45-intCD11bintCD11c+Gr1-_Alzheimer_disease_1_month | 584 | 2.1 | ||||||||||||
11. Whole_brain_5XFAD_CD45-intCD11bintCD11c+Gr1-_Alzheimer_disease_3_months | 122 | 0.6 | ||||||||||||
12. Whole_brain_5XFAD_CD45-intCD11b-intCD11c+Gr1-_Alzheimer_disease_6_months | 380 | 3.6 | ||||||||||||
13. Whole_brain_5XFAD_CD45-intCD11bintCD11c+Gr1-_Alzheimer_disease_9 | 187 | 0.8 | ||||||||||||
14. Whole_brain_5XFAD_CD45-intCD11b-intCD11c+Gr1-_and_CD45-intCD11b-intGr1- | 324 | 1.1 | ||||||||||||
15. Whole_brain_5XFAD_CD45-intCD11b-intGr1-_Alzheimer_disease_6_months_ | 1004 | 1 | ||||||||||||
16. Whole_brain_C57BL_CD45+_Alzheimer_disease_6_months | 6080 | 16 | ||||||||||||
17. Whole_brain_C57BL_CD45+CD11b+Gr1-_Aging_20_months | 760 | 1.7 | ||||||||||||
18. Whole_brain_C57BL_CD45+CD11b+Gr1-_Aging_7_weeks | 1140 | 3.4 | ||||||||||||
19. Whole_brain_C57BL_CD45-intCD11b-intCD11c+Gr1-_Aging_20_months | 155 | 0.7 | ||||||||||||
20. Whole_brain_C57BL_CD45-intCD11b-intCD11c+Gr1-_Alzheimer_disease_6 | 760 | 0.6 | ||||||||||||
21. Whole_brain_C57BL_CD45-intCD11bintGr1-_Alzheimer_disease_1_month | 380 | 2.1 | ||||||||||||
22. Whole_brain_C57BL_CD45-intCD11bintGr1-_Alzheimer_disease_3_months | 380 | 1.5 | ||||||||||||
23. Whole_brain_C57BL_CD45-intCD11b-intGr1-_Alzheimer_disease_6_months | 327 | 2.1 | ||||||||||||
24. Whole_brain_C57BL_CD45-intCD11b-intGr1-_Alzheimer_disease_8_months | 380 | 1.2 | ||||||||||||
25. Whole_brain_Trem2KO_5XFAD_CD45-intCD11b-intCD11c+Gr1-_Alzheimer_disease_6_months | 1140 | 2.9 | ||||||||||||
26. Whole_brain_Trem2KO_5XFAD_CD45-intCD11b-intGr1-_Alzheimer_disease_6_months | 1140 | 3.6 | ||||||||||||
27. Whole_brain_Trem2KO_CD45-intCD11b-intCD11c+Gr1-_Alzheimer_disease_6_months | 272 | 0.7 | ||||||||||||
28. Whole_brain_Trem2KO_CD45-intCD11b-intGr1-_Alzheimer_disease_6_months | 535 | 2.6 | ||||||||||||
GSE89405 | Gene expression profiles for key stages of T cell differentiation | Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing. | Kakaradov ... Yeo Nat Immunol. 2017 | Mus musculus | In Process | 304 | 0 |
GSE94383 | RAW 264.7 Cell Line (murine Macrophage) stimulated with LPS on a fluidigm C1 chip | Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-kB Activation. | Lane ... Covert Cell Syst. 2017 | Mus musculus | In Process | 839 | 0 |
GSE89405 | Gene expression profiles for key stages of T cell differentiation | Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing. | Kakaradov ... Yeo Nat Immunol. 2017 | Mus musculus | In Process | 304 | 0 |
GSE112903 | Droplet-based scRNAseq on sorted mouse pLN CD45- CD31- cells from uninfected mice and mice at day 15 post-infection with LCMV-Armstrong | Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity | Rodda ... Cyster Immunity 2018 | Mus musculus | In Process | 0 | 0 |
GSE106973 | Single cell RNA sequencing of murine basophil/mast cell progenitors and granulocyte/monocyte progenitors | A single-cell hematopoietic landscape resolves 8 lineagetrajectories and defects in Kit mutant mice. | Dahlin ... Wilson Blood 2018 | Mus musculus | In Process | 141 | 0 |
GSE107727 | Single cell RNA sequencing of murine basophil/mast cell progenitors and granulocyte/monocyte progenitors | A single-cell hematopoietic landscape resolves 8 lineagetrajectories and defects in Kit mutant mice. | Dahlin ... Wilson Blood 2018 | Mus musculus | In Process | 44802 | 0 |
GSE104054 | Single cells from the specific immune niches in the lymph node and spleen | Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq | Medaglia ... Amit Science 2017 | Mus musculus | In Process | 0 | 0 |
E-MTAB-6051 | Single-cell RNA sequencing of OT-I CD8+ T cells after stimulation with different affinity | T cell cytolytic capacity is independent of initial stimulation strength | Richard ... Griffiths Nat Immunol. 2018 | Mus musculus | In Process | 572 | 0 |
GSE114895 | Thymic tuft cell single-cell mRNA analysis | Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development | Miller ... Anderson Nature 2018 | Mus musculus | In Process | 300 | 0 |
GSE103967 | Transcriptional profiling of single cells from the stroma of mouse thymus | Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells | Bornstein ... Amit Nature 2018 | Mus musculus | In Process | 0 | 0 |
GSE103968 | Transcriptional profiling of single cells from the stroma of mouse thymus | Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells | Bornstein ... Amit Nature 2018 | Mus musculus | In Process | 0 | 0 |
GSE111664 | Drop-seq analysis of bleomycin-treated and control mouse lung single-cell suspensions | Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage | Aran ... Bhattacharya Nat Immunol 2019 | Mus musculus | In Process | 0 | 0 |
E-MTAB-7142 | Drop-seq analysis of bleomycin-treated and control mouse lung single-cell suspensions | Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage | Aran ... Bhattacharya Nat Immunol 2019 | Mus musculus | In Process | 0 | 0 |
GSE118948 | CD45+ cells isolated from different CNS compartments (including leptomeninges, perivascular space and parenchyma, and choroid plexus) and Ly6Chigh and Ly6Clow monocytes from blood | Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. | Jord?o ... Prinz Science 2019 | Mus musculus | In Process | 0 | 0 |
GSE125044 | single cells from pathogen-injected mouse auricular lymph nodes | Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity | Blecher-Gonen ... Amit Cell Syst 2019 | Mus musculus | In Process | 0 | 0 |
GSE128985 | Time course RNA-seq profiling in sorted endothelial, epithelial, immune, and mesenchymal-derived cells from E16.5, E18.5, P7 and P28 wild-type C57BL6 mice | Whitsett ... Xu 2019 | Mus musculus | In Process | 0 | 0 |
GSE108892 | SubSeries: GSE108891, GSE118436 | The bone marrow microenvironment at single-cell resolution | Tikhonova ... Aifantis Nature 2019 | Mus musculus | In Process | 0 | 0 |
GSE127005 | Single cell transcriptomic analysis (InDrops) of mouse mesenchymal stromal cells (mSCs or FAPs, fibro-adipogenic progenitors) isolated from lymph node, muscle and visceral adipose tissue | Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors | Spallanzan ... Mathis Science Immunology 2019 | Mus musculus | In Process | 0 | 0 |
GSE128855 (GSE128854 ) | single-cell atlas of mouse brain macrophages | A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shapedby ontogeny and tissue environment | Van Hove ... Movahedi Nat Neurosci. 2019 | Mus musculus | In Process | 0 | 0 |
GSE92495 | Profile thousands of primary human macrophages exposed to tuberculosis. | Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. | Gierahn ... Shalek Nat Methods 2017 | Homo sapiens; Mus musculus | In Process | 96 | 0 |
GSE99068 | RNA sequencing of two types of NK cells from mouse and human (IL6Ra negative NK cells vs. IL6Ra positive NK cells) and mouse organs (IL6Ra_NKdel vs. IL6Ra_NKflox) | IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis | Theurich ... Bruning Cell Metab. 2017 | Homo sapiens; Mus musculus | In Process | 63 | 0 |
GSE119562 | Natural Killer cell heterogeneity in humans and mice | High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NKCell Subsets in Humans and Mice | Crinier ... Vivier Immunity 2018 | Homo sapiens; Mus musculus | In Process | 0 | 0 |
GSE127465 | scRNAseq of RBC-depleted cells from non-small cell lung tumor and from blood of 7 patients. ScRNAseq of CD45-positive cells from lungs of 2 healthy mice and 2 lung tumor-bearing mice | Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species | Zilionis ... Klein Immunity 2019 | Homo sapiens; Mus musculus | In Process | 0 | 0 |
GSE97168 | Human stage IA lung adenocarcinoma lesion and adjacent non-involved lung | Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses | Lavin ... Merad Cell 2017 | Homo sapiens (hg38) | 2 | 1920 | 7.5 |
1. lung | 768 | 2.8 | ||||||||||||
2. tumor | 1152 | 4.6 | ||||||||||||
GSE75659 | Human T-cells. Mouse fibroblasts from this experiment can be found in the non-immune part. | Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq | Reinius ... Sandberg Nature Genetics 2016 | Homo sapiens (hg38) | 3 | 892 | 105 |
1. Tcell.ex.vivo | 347 | 58.5 | ||||||||||||
2. Tcell.in.vivo.D136 | 73 | 7.9 | ||||||||||||
2. Tcell.in.vivo.D15 | 472 | 38.5 | ||||||||||||
CD14+ Monocytes | CD14+ Monocytes enriched from fresh PBMCs. | Massively parallel digital transcriptional profiling of single cells. | Zheng ... Bielas Nat Commun 2017 | Homo sapiens (hg38) | 1 | 2612 | 8.2 |
CD56+ Natural Killer Cells | CD56+ NK cells enriched from fresh PBMCs. 92% pure by FACS | Massively parallel digital transcriptional profiling of single cells. | Zheng ... Bielas Nat Commun 2017 | Homo sapiens (hg38) | 1 | 8385 | 12.7 |
GSE75478 | Single-cell indexed RNA-Seq of human hematopoietic stem and progenitors | Human haematopoietic stem cell lineage commitment is a continuous process. | Velten ... Steinmetz Nat Cell Biol. 2017 | Homo sapiens (hg38) | 5 | 2414 | 377.9 |
1. Lin-CD34+CD38+CD45RA-CD90+_QUARTZ-Seq | 96 | 18.8 | ||||||||||||
2. Lin-CD34+CD38+_QUARTZ-Seq | 384 | 74.5 | ||||||||||||
3. Lin-CD34+CD38-_smart-seq2 | 526 | 65.2 | ||||||||||||
4. Lin-CD34+CD38+_smart-seq2 | 736 | 89.4 | ||||||||||||
5. Lin-CD34+CD38-_QUARTZ-Seq | 672 | 130 | ||||||||||||
GSE100618 | Single Cell RNA sequencing analysis of human haemopoietic lympho-myeloid progenitor populations (LMPP, MLP and GMP) | Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells | Karamitros ... Vyas Nat Immunol. 2017 | Homo sapiens (hg38) | 4 | 420 | 118 |